| Western Terminus |

The western terminus of MS 6 is on MS 161 in Clarksdale. Just east of this intersection, MS 6 begins its long duplex with US 278. Photo by Robert Lee on 3/4/2006.
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| Change of Maintenance #1 - MS 145, Tupelo |

US 278/MS 6 changes from MDOT maintenance to City of Tupelo maintenance at the intersection of MS 145. Photo taken by Robert Lee on 11/20/2005.
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| Change of Maintenance #2 - Elizabeth St., Tupelo |

Maintenance of US 278/MS 6 returns to MDOT at Elizabeth Street, just west of US 45. Photo taken by Robert Lee on 11/20/2005.
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| Eastern Terminus |

The eastern terminus of MS 6 is on MS 25 in Amory. Photo by Robert Lee.
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